Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10556550 | 0.91 | MEN1 (0.61) | CHRM4SIGMAR1SLC18A3MEN1KMT2A | |
| SCHEMBL7329656 | 0.86 | MEN1 (0.74) | CHRM4SIGMAR1SLC18A3MEN1KMT2A | |
| SCHEMBL29869413 | 0.84 | MEN1 (0.54) | CHRM4SIGMAR1SLC18A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11499589 | 0.82 | MEN1 (0.52) | CHRM4SIGMAR1SLC18A3MEN1KMT2A | |
| SCHEMBL6994717 | 0.80 | HTR2A (0.64) | SIGMAR1HTR2A | |
| SCHEMBL19493714 | 0.79 | SLC18A3 (0.70) | SIGMAR1SLC18A3MEN1KMT2A | |
| SCHEMBL5577360 | 0.78 | MCHR1 (0.60) | CHRM4SIGMAR1MEN1KMT2AHTR2A | |
| SCHEMBL30567998 | 0.77 | DRD2 (0.62) | SIGMAR1HRH3HTR2A | |
| Hydrochloric Acid SCHEMBL9811466 | 0.77 | DRD2 (0.61) | SIGMAR1SLC18A3KMT2AHTR2A | |
| SCHEMBL7179272 | 0.77 | MEN1 (0.68) | CHRM4SIGMAR1MEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |