Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.68 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19493714 | 0.92 | SLC18A3 (0.70) | MEN1KMT2ASLC18A3SIGMAR1BCHE | |
| SCHEMBL10556550 | 0.92 | MEN1 (0.61) | MEN1KMT2ASLC18A3SIGMAR1BCHE | |
| SCHEMBL1002852 | 0.88 | MEN1 (0.81) | MEN1KMT2ASLC18A3SIGMAR1ACHE | |
| Oxalic Acid SCHEMBL7329508 | 0.86 | CHRM4 (0.60) | MEN1KMT2ASLC18A3SIGMAR1CHRM4 | |
| SCHEMBL16227271 | 0.86 | TRPV6 (0.74) | MEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL29869413 | 0.84 | MEN1 (0.54) | MEN1KMT2ASLC18A3SIGMAR1BCHE | |
| SCHEMBL8775737 | 0.84 | MEN1 (0.74) | MEN1KMT2ASLC18A3SIGMAR1ACHE | |
| SCHEMBL2332535 | 0.84 | MEN1 (0.74) | MEN1KMT2ASLC18A3SIGMAR1DRD2 | |
| SCHEMBL19222078 | 0.84 | MEN1 (0.74) | MEN1KMT2ASLC18A3SIGMAR1ACHE | |
| SCHEMBL3153917 | 0.84 | MEN1 (0.74) | MEN1KMT2ASLC18A3SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |