Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27861923 | 0.94 | NOTUM (0.45) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL21609843 | 0.90 | NOTUM (0.60) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL29659866 | 0.90 | NOTUM (0.60) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL28667831 | 0.83 | POLB (0.51) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL29144762 | 0.82 | CA1 (0.56) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6002200 | 0.79 | EPAS1 (0.49) | NOTUMLMNAALDH1A1EPAS1MEN1 | |
| SCHEMBL7286109 | 0.78 | EPAS1 (0.48) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL732952 | 0.77 | NOTUM (0.45) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL3343549 | 0.77 | CA12 (0.52) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL732949 | 0.77 | LCK (0.57) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120569-B1 | SPIROCHROMANON DERIVATIVES | MERCK SHARP & DOHME (US) | 2013-08-14 | — | — | EP | disclosed |
| US-8138197-B2 | Spirochromanon derivatives | MSD K.K. (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-2120569-A2 | SPIROCHROMANON DERIVATIVES | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008088692-A2 | SPIROCHROMANON DERIVATIVES | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-1333050-B1 | MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME | SUMITOMO BAKELITE CO (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-7049371-B2 | Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-6949674-B2 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| US-20040002572-A1 | Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2004-01-01 | — | — | US | disclosed |
| EP-1346975-A1 | AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH | SUMITOMO BAKELITE CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |
| EP-1333050-A1 | MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME | SUMITOMO BAKELITE CO., LTD. (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1327653-A1 | HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE | SUMITOMO BAKELITE CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6518390-B2 | Polybenzoxazole and crosslinking agent | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| US-20020013443-A1 | Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device | SUMITOMO BAKELITE CO., LTD. (JP) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | CCR1, CCRL2, CCR6 | NOTUM 2645/4885CA12 1958/4885CA1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.