Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329781 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL494763 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL6057206 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL494288 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL466419 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL495310 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL496221 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154041 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154814 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 | |
| SCHEMBL2154590 | 1.00 | TSHR (0.72) | TSHRALDH1A1TP53LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118993888-A | Preparation method of mono-tert-butyl octadecanedioate | 苏州昊帆生物股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-3184171-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-12-04 | — | — | US | disclosed |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-10-26 | — | — | US | disclosed |
| US-9732106-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-08-15 | — | — | US | disclosed |
| EP-3184171-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2017100045-A1 | FLUORINATED PIPERAZINE SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100045-A1 | FLUORINATED PIPERAZINE SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-15 | — | — | WO | disclosed |
| EP-2519532-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2017-03-08 | — | — | EP | disclosed |
| US-9464183-B2 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20080047650-A1 | Rubber Composition And Pneumatic Tire Using The Same | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1820667-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1724252-A1 | COMPOUND AND COMPOSITION CONTAINING THE SAME | Mitsui Chemicals, Inc. (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1724302-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-20060205971-A1 | Compound and composition containing the same | MITSUI CHEMICALS, INC. (JP) | 2006-09-14 | — | — | US | disclosed |
| EP-0700909-B1 | Photosensitive bis(halomethyloxadiazole) compound and photosensitive transfer sheet using the same | FUJI PHOTO FILM CO LTD (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |
| US-4067860-A | N,N'-bis(3,4-dicyanophenyl) alkanediamide, polyphthalocyanines, and preparation thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1978-01-10 | — | — | US | disclosed |
| US-4056560-A | COATINGS, LAMINATES, ADHESIVES, CASTINGS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1977-11-01 | — | — | US | disclosed |
| US-3993631-A | Polyphthalocyanines prepared from N,N-bis(3,4-dicyanophenyl) alkanediamides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | NIT2, NCLN, NPM1 | TSHR 3542/4885ALDH1A1 4849/4885TP53 1644/4885 |
| US-20060205971-A1 | Compound and composition containing the same | RFC4, RFC5, RFC1 | TSHR 4491/4885ALDH1A1 1041/4885TP53 2205/4885 |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | TSHR 3542/4885ALDH1A1 4849/4885TP53 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.