Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.58 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.58 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18983076 | 0.83 | KMT2A (0.65) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25983244 | 0.83 | KMT2A (0.65) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL143 | 0.82 | CES1 (0.53) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL3271740 | 0.79 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3074392 | 0.79 | KMT2A (0.74) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17115264 | 0.79 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL229650 | 0.79 | KMT2A (1.00) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6246649 | 0.79 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| Bromide SCHEMBL28972076 | 0.78 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL28839155 | 0.78 | CES1 (0.50) | KMT2AMEN1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| WO-2024042448-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB | GRANULES INDIA LIMITED (IN) | 2024-02-29 | — | — | WO | claimed |
| EP-3985008-A1 | PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR | Incyte Holdings Corporation (US) | 2022-04-20 | — | — | EP | claimed |
| CN-111875607-B | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2021-12-03 | — | — | CN | claimed |
| US-20210253584-A1 | Processes for Preparing Jak Inhibitors and Related Intermediate Compounds | INCYTE HOLDINGS CORPORATION | 2021-08-19 | — | — | US | claimed |
| EP-3398952-B1 | SYNTHESIS PROCESS OF RUXOLITINIB | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-07-14 | — | — | EP | claimed |
| EP-3473625-B1 | PREPARATION METHOD FOR CHIRAL PYRROLOPYRIMIDINE COMPOUND | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-06-02 | — | — | EP | claimed |
| CN-111875607-A | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2020-11-03 | — | — | CN | claimed |
| US-10766901-B2 | Preparation method for chiral pyrrolopyrimidine compound | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-09-08 | — | — | US | claimed |
| CN-109311892-B | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| EP-0983237-A1 | CHEMICAL PROCESS FOR THE REDUCTION OF 1-SUBSTITUTED -3-HYDROXYMETHYL-4- (4-FLUOROPHENYL)TETRAHYDROPYRIDINES | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-03-08 | — | — | EP | claimed |
| WO-1998052920-A1 | CHEMICAL PROCESS FOR THE REDUCTION OF 1-SUBSTITUTED -3-HYDROXYMETHYL-4- (4-FLUOROPHENYL)TETRAHYDROPYRIDINES | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | claimed |
| EP-0474789-B1 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | GENETIC SYSTEMS CORP (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0788487-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | Novartis AG (CH) | 1997-08-13 | — | — | EP | claimed |
| WO-1996013489-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | NOVARTIS AG (CH) | 1996-05-09 | — | — | WO | claimed |
| US-5439792-A | Synthesizing a cyclic viral protein epitope | GENETIC SYSTEMS CORPORATION (US) | 1995-08-08 | — | — | US | claimed |
| US-5360928-A | Synthesis and use of amino acid fluorides as peptide coupling reagents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-11-01 | — | — | US | claimed |
| EP-0474789-A4 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | — | 1992-06-03 | — | — | EP | claimed |
| EP-0474789-A1 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | GENETIC SYSTEMS CORPORATION (US) | 1992-03-18 | — | — | EP | claimed |
| WO-1990015071-A1 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | GENETIC SYSTEMS CORPORATION (US) | 1990-12-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253584-A1 | Processes for Preparing Jak Inhibitors and Related Intermediate Compounds | JAK3, JAK1, JAK2 | KMT2A 1913/4885MEN1 3188/4885ALDH1A1 3122/4885 |
| US-10766901-B2 | Preparation method for chiral pyrrolopyrimidine compound | DHPS, DPYD, MPHOSPH6 | KMT2A 2265/4885MEN1 2666/4885ALDH1A1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.