SCHEMBL733010

SCHEMBL733010

O=C=Nc1ccc(CCc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.74
TSHR P16473 2/20 0.74
P2RY6 Q15077 1/20 0.60
CYP1A2 P05177 1/20 0.52
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TRPA1 O75762 1/20 0.42
GFER P55789 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
NOS3 P29474 2/20 0.33
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
AOC3 Q16853 1/20 0.33
FFAR1 O14842 1/20 0.32
CA2 P00918 2/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11061694 0.93 CYP3A4 (0.65) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL4600058 0.91 CYP3A4 (0.63) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL7898757 0.91 CYP3A4 (0.68) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL1900351 0.91 CYP3A4 (0.68) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL16372530 0.89 CYP3A4 (0.61) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL18126137 0.89 CYP3A4 (0.61) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL11723360 0.89 CYP3A4 (0.65) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL93144 0.87 CYP3A4 (0.63) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL3989130 0.87 CYP3A4 (0.63) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL27930613 0.87 CYP3A4 (0.63) CYP3A4TSHRP2RY6CYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1592 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902889-B1 THERMOPLASTIC POLYURETHANE HOT-MELT ADHESIVE AND ITS USE BASF SE (DE) 2026-03-25 EP claimed
EP-4667504-A1 SPRAYING-FREE MEMORY NANO NYLON RESIN AND PREPARATION METHOD THEREOF Shenzhen Keruishi Optics Technology Co., Ltd. (CN) 2025-12-24 EP claimed
EP-4615923-A1 BONDING OF PARTS TO AN ARTICLE AND SEPARATING THE ARTICLE FOR RECYCLING BASF SE (DE) 2025-09-17 EP claimed
US-12337542-B2 Three-dimensional printing device for printing polyurethane articles Evoco Limited (CA) 2025-06-24 US claimed
US-20250034317-A1 POLYURETHANE ELASTOMER WITH IMPROVED HYDROLYSIS RESISTANCE COVESTRO DEUTSCHLAND AG (DE) 2025-01-30 US claimed
EP-3581600-B1 RESIN LENS AND PREPARATION METHOD THEREFOR EFIRM NEW MAT CO LTD (CN) 2025-01-08 EP claimed
EP-4444778-A1 POLYURETHANE ELASTOMER WITH IMPROVED HYDROLYSIS RESISTANCE Covestro Deutschland AG (DE) 2024-10-16 EP claimed
WO-2024100018-A1 BONDING OF PARTS TO AN ARTICLE AND SEPARATING THE ARTICLE FOR RECYCLING BASF SE (DE) 2024-05-16 WO claimed
US-20240141093-A1 Polyol and a Process for the Preparation Thereof BASF SE (DE) 2024-05-02 US claimed
EP-4308629-A1 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2024-01-24 EP claimed
US-5102918-A Storage stability; smokeless foam NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 1992-04-07 US claimed
EP-0455585-A1 Unsaturated urea polysiloxanes CIBA-GEIGY AG (CH) 1991-11-06 EP claimed
US-4983702-A Crosslinked siloxane-urethane polymer contact lens CIBA-GEIGY CORPORATION (US) 1991-01-08 US claimed
EP-0353298-A4 POLYURETHANES OF IMPROVED CHARACTERISTICS. HEXCEL CORP (US) 1990-06-27 EP claimed
EP-0362145-A2 Crosslinked siloxane-urethane polymer contact lens CIBA-GEIGY AG (CH) 1990-04-04 EP claimed
EP-0353298-A1 POLYURETHANES OF IMPROVED CHARACTERISTICS HEXCEL CORPORATION (US) 1990-02-07 EP claimed
WO-1989007116-A1 POLYURETHANES OF IMPROVED CHARACTERISTICS HEXCEL CORPORATION (US) 1989-08-10 WO claimed
US-4448946-A HIGHER MOLECULAR WEIGHT POLYHYDROXYL AND LOW MOLECULAR WEIGHT CHAIN EXTENDER; TIRES, GASKETS, SHOE SOLES BASF AKTIENGESELLSCHAFT (DE) 1984-05-15 US claimed
US-4421870-A HIGH DENSITY, HIGH COMPRESSIVE AND TEAR STRENGTH BASF AKTIENGESELLSCHAFT (DE) 1983-12-20 US claimed
EP-0048117-A2 In-mold coating compositions containing a non-isocyanate-reactive unsaturated resin, a non-isocyanate-reactive monomer and a free isocyanate-containing compound ICI AMERICAS INC. (US) 1982-03-24 EP claimed