SCHEMBL7898757

SCHEMBL7898757

O=C=Nc1ccc(CCCCc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.68
TSHR P16473 1/20 0.68
P2RY6 Q15077 1/20 0.50
CYP1A2 P05177 1/20 0.49
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRPA1 O75762 1/20 0.39
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
MAOB P27338 2/20 0.35
SIGMAR1 Q99720 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MIF P14174 1/20 0.34
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
TACR2 P21452 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1900351 0.95 CYP3A4 (0.68) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL22139933 0.92 TSHR (0.59) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL733010 0.91 CYP3A4 (0.74) CYP3A4TSHRP2RY6CYP1A2MAPK1
SCHEMBL1403683 0.90 CYP3A4 (0.57) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1
SCHEMBL5885366 0.89 CYP3A4 (0.55) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1
SCHEMBL13725699 0.89 CYP3A4 (0.55) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1
SCHEMBL673425 0.89 CYP3A4 (0.55) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1
SCHEMBL10400983 0.89 CYP3A4 (0.55) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1
SCHEMBL5885475 0.89 CYP3A4 (0.55) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1
SCHEMBL5884680 0.89 CYP3A4 (0.55) CYP3A4TSHRCYP2D6CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240141093-A1 Polyol and a Process for the Preparation Thereof BASF SE (DE) 2024-05-02 US claimed
EP-4308629-A1 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2024-01-24 EP claimed
EP-4305085-A1 POLYUREA COPOLYMER BASF SE (DE) 2024-01-17 EP claimed
WO-2022194979-A9 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2023-07-20 WO claimed
US-20230092952-A1 POLYUREA COPOLYMER BASF SE (DE) 2023-03-23 US claimed
US-20230062261-A1 POLYUREA COPOLYMER BASF SE (DE) 2023-03-02 US claimed
WO-2021122480-A1 POLYUREA COPOLYMER BASF SE (DE) 2021-06-24 WO claimed
WO-2021122472-A1 POLYUREA COPOLYMER BASF SE (DE) 2021-06-24 WO claimed
US-20240190836-A1 XANTHENE DERIVATIVE COMPOUND HAVING HIGH REFRACTIVE INDEX AND (CO)POLYMER COMPRISING SAME Research & Business Foundation Sungkyunkwan University (KR) 2024-06-13 US disclosed
US-20240141093-A1 Polyol and a Process for the Preparation Thereof BASF SE (DE) 2024-05-02 US disclosed
WO-2024064691-A1 SYSTEM AND METHOD FOR PFAS CONTAINMENT BASF SE (DE) 2024-03-28 WO disclosed
EP-4308629-A1 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2024-01-24 EP disclosed
EP-4305085-A1 POLYUREA COPOLYMER BASF SE (DE) 2024-01-17 EP disclosed
WO-2022194979-A9 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2023-07-20 WO disclosed
US-4169955-A GRAFT POLYMER INTERMEDIATES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-10-02 US disclosed
US-4155824-A ACRYLIC POLYMER CONTAINING OXIRANE GROUPS WHICH HAVE BEEN OPENED WITH A FATTY ACID AND AN AMINE GROW CHEMICAL CORP. (US) 1979-05-22 US disclosed
US-4151227-A Acrylic graft copolymers and coating compositions thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-24 US disclosed
US-4148704-A ADHESION, CORROSION RESISTANCE, GLOSS GROW CHEMICAL CORP. (US) 1979-04-10 US disclosed
US-3998768-A Thermosetting powder coating composition of a blend of acrylic polymers having different glass transition temperatures and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-21 US disclosed
US-3969569-A ALLYL ALCOHOL POLYMER AND A POLYISOCYANATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190836-A1 XANTHENE DERIVATIVE COMPOUND HAVING HIGH REFRACTIVE INDEX AND (CO)POLYMER COMPRISING SAME WEE1, SQLE, WASF2 CYP3A4 2494/4885TSHR 4239/4885P2RY6 1341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.