Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.59 |
| ▸ | CTSS | P25774 | 2/20 | 0.59 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324089 | 0.93 | CTSK (0.57) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL10192146 | 0.93 | CTSK (0.57) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL7324091 | 0.93 | CTSK (0.57) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL7018649 | 0.86 | CTSK (0.63) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL22371977 | 0.86 | CTSK (0.63) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL15671593 | 0.86 | CTSK (0.63) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL22371978 | 0.86 | CTSK (0.63) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL22371979 | 0.86 | CTSK (0.63) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL3087516 | 0.86 | CTSK (0.63) | CTSKCTSSPSENENPREPCA2 | |
| SCHEMBL30064660 | 0.86 | CTSK (0.59) | CTSKCTSSPSENENPREPCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |