SCHEMBL7330245

SCHEMBL7330245

CO/N=C/c1ccc(O)c(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.71
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
TRPA1 O75762 1/20 0.61
TRIM24 O15164 1/20 0.61
ALDH5A1 P51649 1/20 0.61
ABAT P80404 1/20 0.61
TRIM33 Q9UPN9 1/20 0.61
AMY1A P0DUB6 1/20 0.59
TYR P14679 2/20 0.59
NFKB1 P19838 3/20 0.58
NFKB2 Q00653 3/20 0.58
RELA Q04206 3/20 0.58
NFE2L2 Q16236 3/20 0.58
CYP2D6 P10635 3/20 0.58
CYP1A2 P05177 3/20 0.58
ALOX5 P09917 2/20 0.58
HSD11B1 P28845 2/20 0.58
STAT3 P40763 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7330250 1.00 SRC (0.71) SRCALDH1A1HPGDTDP1TRPA1
Hydrochloric Acid SCHEMBL7331650 0.98 SRC (0.69) SRCALDH1A1HPGDTDP1TRPA1
Hydrochloric Acid SCHEMBL7331647 0.98 SRC (0.69) SRCALDH1A1HPGDTDP1TRPA1
SCHEMBL12756980 0.86 CYP1A2 (0.74) SRCALDH1A1CYP1A2ALOX5KMT2A
SCHEMBL31021335 0.85 MAPT (0.73) ALDH1A1HPGDTDP1TRPA1TRIM24
SCHEMBL591866 0.85 MAPT (0.73) ALDH1A1HPGDTDP1TRPA1TRIM24
SCHEMBL16864095 0.84 ALDH1A1 (0.62) ALDH1A1HPGDTDP1TRPA1TRIM24
SCHEMBL7990948 0.84 ALDH1A1 (0.62) ALDH1A1HPGDTDP1TRPA1TRIM24
SCHEMBL5075035 0.84 ALDH1A1 (0.62) ALDH1A1HPGDTDP1TRPA1TRIM24
SCHEMBL2568930 0.84 ALDH1A1 (0.62) ALDH1A1HPGDTDP1TRPA1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4570006-A ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS TORII & CO. LTD. (JP) 1986-02-11 US disclosed
US-4514416-A Amidine compound, process for producing same and anti-complement agent comprising same TORII & CO. LTD. (JP) 1985-04-30 US disclosed