Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10058175 | 1.00 | TLR8 (0.35) | TLR8ALOX5BCHEPGK1PGK2 | |
| SCHEMBL5800572 | 0.82 | CYP19A1 (0.46) | ALOX5ALDH1A1TYRLMNACYP3A4 | |
| SCHEMBL7329199 | 0.79 | F13A1 (0.47) | ALDH1A1LMNAMAPT | |
| SCHEMBL7319898 | 0.79 | F13A1 (0.47) | ALDH1A1LMNAMAPT | |
| SCHEMBL7330244 | 0.79 | F13A1 (0.47) | ALDH1A1LMNAMAPT | |
| SCHEMBL7328264 | 0.75 | ALOX5 (0.36) | ALOX5BCHEALDH1A1TYRLMNA | |
| SCHEMBL10547778 | 0.75 | ALOX5 (0.50) | ALOX5TNKS2LMNAPGRCYP3A4 | |
| SCHEMBL10058345 | 0.75 | HPGD (0.43) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL15725312 | 0.74 | TLR8 (0.40) | TLR8PGK1PGK2ALDH1A1TNKS2 | |
| SCHEMBL7408439 | 0.73 | ALOX5 (0.52) | ALOX5TNKS2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-51128932-A | — | — | None | — | — | JP | disclosed |
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |
| JP-S51128932-A | ORGANIC COMPOUNDS | TAKEDA CHEM IND LTD | 1976-11-10 | — | — | JP | disclosed |