Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciprokiren SCHEMBL7530263 | 0.91 | REN (0.61) | REN | |
| Ciprokiren SCHEMBL564425 | 0.91 | REN (0.61) | REN | |
| SCHEMBL7329846 | 0.88 | REN (0.50) | REN | |
| SCHEMBL7534258 | 0.88 | REN (0.54) | REN | |
| SCHEMBL7436746 | 0.85 | REN (0.55) | REN | |
| SCHEMBL7534571 | 0.85 | REN (0.57) | REN | |
| SCHEMBL7344088 | 0.85 | REN (0.62) | REN | |
| SCHEMBL7335680 | 0.85 | REN (0.63) | REN | |
| SCHEMBL7535138 | 0.85 | REN (0.63) | REN | |
| SCHEMBL7532148 | 0.84 | REN (0.51) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509354-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-23 | — | — | EP | disclosed |
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0509354-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-21 | — | — | EP | disclosed |