SCHEMBL7534571

SCHEMBL7534571

CC(C)[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)CS(=O)(=O)C(C)(C)C(=O)N1CCOCC1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciprokiren SCHEMBL7530263 0.94 REN (0.61) REN
Ciprokiren SCHEMBL564425 0.94 REN (0.61) REN
SCHEMBL9287920 0.88 REN (0.69) REN
SCHEMBL7281295 0.88 REN (0.69) REN
SCHEMBL7534258 0.88 REN (0.54) REN
SCHEMBL7436746 0.88 REN (0.55) REN
SCHEMBL7344088 0.88 REN (0.62) REN
SCHEMBL7335680 0.87 REN (0.63) REN
SCHEMBL7535138 0.87 REN (0.63) REN
SCHEMBL8239586 0.87 REN (0.49) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509354-B1 Amino acid derivatives HOFFMANN LA ROCHE (CH) 2000-08-23 EP disclosed