Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | GALR3 | O60755 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327269 | 0.91 | F2 (0.66) | F2KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL7359983 | 0.91 | ROCK2 (0.62) | F2KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL8548599 | 0.91 | F2 (0.68) | F2KMT2AMEN1KDM4ELMNA | |
| SCHEMBL8543743 | 0.91 | F2 (0.68) | F2KMT2AMEN1KDM4ELMNA | |
| SCHEMBL8544004 | 0.88 | F2 (0.70) | F2KMT2AMEN1KDM4ELMNA | |
| SCHEMBL8548228 | 0.85 | KMT2A (0.59) | F2KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL7335988 | 0.85 | MAPT (0.63) | F2KMT2AMEN1KDM4ELMNA | |
| SCHEMBL7357930 | 0.85 | KMT2A (0.55) | F2KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL7325645 | 0.82 | F2 (0.60) | F2SMN1; SMN2LMNAGAAPKM | |
| Hydrochloric Acid SCHEMBL8542002 | 0.81 | F2 (0.98) | F2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |