Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | GALR3 | O60755 | 2/20 | 0.68 |
| ▸ | STAT3 | P40763 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327269 | 0.90 | F2 (0.66) | F2LMNAGALR3STAT3KMT2A | |
| SCHEMBL7330380 | 0.88 | F2 (0.69) | F2LMNAGALR3STAT3KMT2A | |
| SCHEMBL8543743 | 0.88 | F2 (0.68) | F2LMNAGALR3STAT3KMT2A | |
| SCHEMBL8548599 | 0.88 | F2 (0.68) | F2LMNAGALR3POLBKMT2A | |
| SCHEMBL7329316 | 0.86 | LMNA (0.59) | F2LMNAGALR3STAT3CYP1A2 | |
| SCHEMBL7359983 | 0.86 | ROCK2 (0.62) | F2LMNAPOLBKMT2AMEN1 | |
| SCHEMBL7357930 | 0.84 | KMT2A (0.55) | F2LMNAGALR3STAT3POLB | |
| SCHEMBL7324125 | 0.83 | F2 (0.60) | F2LMNAKMT2AMEN1PKM | |
| SCHEMBL8544836 | 0.82 | F2 (1.00) | F2KMT2AMEN1 | |
| SCHEMBL7336884 | 0.80 | GALR3 (0.64) | LMNAGALR3STAT3POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |