Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5076556 | 1.00 | CA1 (0.39) | CA1CA2CYP1A2ZDHHC7CPB2 | |
| SCHEMBL6873312 | 0.92 | CPB2 (0.46) | CA1CA2ZDHHC7CPB2GSR | |
| SCHEMBL1555156 | 0.86 | — | — | |
| SCHEMBL7741435 | 0.86 | — | — | |
| SCHEMBL1556637 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL5317901 | 0.84 | GABRR1 (0.38) | CA1CA2CYP1A2ZDHHC7CPB2 | |
| Hydrochloric Acid SCHEMBL1094574 | 0.84 | GABRR1 (0.38) | CA1CA2CYP1A2ZDHHC7CPB2 | |
| SCHEMBL7947554 | 0.80 | CA2 (0.61) | CA1CA2ZDHHC7GPR84FFAR1 | |
| SCHEMBL149523 | 0.80 | CA2 (0.61) | CA1CA2ZDHHC7GPR84FFAR1 | |
| SCHEMBL29253175 | 0.80 | CA1 (0.41) | CA1CA2ZDHHC7SMN1; SMN2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147975-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |