Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | F7 | P08709 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324617 | 0.96 | ALDH1A1 (0.49) | ALDH1A1F2F10PRSS1F7 | |
| SCHEMBL7345716 | 0.83 | PLAU (0.53) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL7324570 | 0.81 | MAPT (0.61) | PRSS1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL7339820 | 0.81 | FTO (0.56) | ALDH1A1F2F10PRSS1MAPT | |
| SCHEMBL4766309 | 0.79 | SMN1; SMN2 (0.62) | CYP3A4MAPTPLAULMNAHDAC3 | |
| SCHEMBL102375 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTTP53PLAULMNA | |
| SCHEMBL7332318 | 0.78 | MAPT (0.58) | PRSS1CYP3A4MAPTPLAUMEN1 | |
| SCHEMBL7324273 | 0.77 | MAPT (0.58) | F10PRSS1CYP3A4MAPTPLAU | |
| SCHEMBL6376622 | 0.76 | NPC1 (0.52) | ALDH1A1CYP3A4MAPTTP53PLAU | |
| SCHEMBL7339823 | 0.76 | PLAU (0.52) | F2F10PLAUHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |