Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223672 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL9217451 | 0.82 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7331297 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL8648337 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2B | |
| Iodide SCHEMBL9225689 | 0.81 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL8692845 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7284509 | 0.79 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7283142 | 0.79 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL8648608 | 0.79 | ITGB3 (0.72) | ITGB3ITGA2B | |
| SCHEMBL8693074 | 0.79 | ITGB3 (0.72) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | claimed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |