Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9223672 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL7330638 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL8379580 | 0.74 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL8648337 | 0.74 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL8692845 | 0.73 | ITGB3 (0.74) | ITGB3ITGA2B | |
| SCHEMBL8882929 | 0.72 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL28513535 | 0.70 | LTA4H (0.32) | — | |
| SCHEMBL7331297 | 0.70 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7284509 | 0.69 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7283142 | 0.69 | ITGB3 (1.00) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |