Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | GABRP | O00591 | 2/20 | 0.51 |
| ▸ | GABRD | O14764 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.51 |
| ▸ | GABRE | P78334 | 2/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19268077 | 0.87 | GABRP (0.47) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL11835391 | 0.86 | KDM4E (0.60) | KDM4EHSD17B10GABRPGABRDGABRA1 | |
| SCHEMBL7324248 | 0.83 | GABRP (0.75) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7328152 | 0.83 | GABRP (0.57) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23881573 | 0.81 | KDM4E (0.56) | KDM4EMAPTGAALMNAALDH1A1 | |
| SCHEMBL30089323 | 0.81 | KDM4E (0.56) | KDM4EMAPTGAALMNAALDH1A1 | |
| SCHEMBL11822995 | 0.80 | KDM4E (0.63) | KDM4EHSD17B10MAPTGAALMNA | |
| SCHEMBL11626329 | 0.79 | GABRP (0.44) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11827090 | 0.78 | MAPT (0.72) | KDM4EHSD17B10MAPTGAALMNA | |
| SCHEMBL11824528 | 0.78 | GABRP (0.71) | KDM4EHSD17B10GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000151-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000153-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3987052-A | SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3933794-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |