Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CCR9 | P51686 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705629 | 0.87 | KCNMA1 (0.67) | MAPTLMNATP53KMT2AHTT | |
| SCHEMBL11827090 | 0.87 | MAPT (0.72) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL31000396 | 0.87 | MAPT (0.72) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL10952995 | 0.84 | TP53 (0.53) | MAPTLMNATP53KMT2AHTT | |
| SCHEMBL19010188 | 0.82 | TP53 (0.60) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL610759 | 0.81 | ALDH1A1 (0.53) | MAPTLMNATP53KMT2AHTT | |
| SCHEMBL5782330 | 0.81 | MAPT (0.55) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL11835391 | 0.80 | KDM4E (0.60) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL7330681 | 0.80 | KDM4E (0.60) | KDM4EHSD17B10MAPTLMNATP53 | |
| SCHEMBL9469411 | 0.79 | KDM4E (0.77) | KDM4EHSD17B10MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000153-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000151-A | TRANQUILIZERS, SEDATIVES | THE UPJOHN COMPANY (US) | 1976-12-28 | — | — | US | disclosed |