Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.66 |
| ▸ | MMP2 | P08253 | 11/20 | 0.66 |
| ▸ | MMP3 | P08254 | 9/20 | 0.66 |
| ▸ | MMP8 | P22894 | 6/20 | 0.65 |
| ▸ | MMP9 | P14780 | 5/20 | 0.65 |
| ▸ | MMP7 | P09237 | 4/20 | 0.65 |
| ▸ | FCER2 | P06734 | 4/20 | 0.65 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.58 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | MMP14 | P50281 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28221967 | 1.00 | MMP1 (0.66) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL7330972 | 1.00 | MMP1 (0.66) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL10036418 | 0.92 | MMP1 (0.58) | MMP1MMP2MMP3MMP8MMP9 | |
| SCHEMBL30051537 | 0.89 | LTA4H (0.61) | MMP2MMP9MMP7MMP12MMP13 | |
| SCHEMBL2185269 | 0.89 | LTA4H (0.64) | MMP2MMP9MMP7MMP12MMP13 | |
| SCHEMBL28860411 | 0.89 | LTA4H (0.64) | MMP2MMP9MMP7MMP12MMP13 | |
| SCHEMBL1864709 | 0.89 | LTA4H (0.64) | MMP2MMP9MMP7MMP12MMP13 | |
| SCHEMBL27517670 | 0.89 | LTA4H (0.64) | MMP2MMP9MMP7MMP12MMP13 | |
| SCHEMBL29519583 | 0.89 | LTA4H (0.64) | MMP2MMP9MMP7MMP12MMP13 | |
| SCHEMBL20669159 | 0.89 | MMP1 (0.61) | MMP1MMP2MMP3MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |