Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444401 | 0.85 | MEN1 (0.59) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL246473 | 0.85 | MEN1 (0.59) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL6964948 | 0.85 | TAAR1 (0.54) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL24242076 | 0.84 | MAOB (0.44) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL8343080 | 0.84 | TAAR1 (0.44) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL9220937 | 0.83 | IAPP (0.55) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL2859015 | 0.83 | TAAR1 (0.57) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL2527059 | 0.83 | TAAR1 (0.52) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL30799043 | 0.83 | TAAR1 (0.52) | TAAR1CASP3CASP7ALDH1A1MEN1 | |
| SCHEMBL11549937 | 0.83 | TAAR1 (0.52) | TAAR1CASP3CASP7ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083686-B | The method of alpha-brominated acetophenone oxime ether synthesis 2,4- diaryl pyrrole class compound | 苏州大学 | 2019-01-22 | — | — | CN | claimed |
| CN-105801550-A | Novel benzopyran kinase modulators | 理森制药股份公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105801550-B | Novel chromene kinase modulator | 理森制药股份公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109293652-A | A kind of substituted thiazole and application thereof | 四川科伦博泰生物医药股份有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-106083686-B | The method of alpha-brominated acetophenone oxime ether synthesis 2,4- diaryl pyrrole class compound | 苏州大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-105164134-B | It is used as the imidazo-triazine derivative of PDE10 inhibitor | 辉瑞大药厂 | 2017-09-22 | — | — | CN | disclosed |
| CN-106687136-A | Combination alzheimer therapy using anti-N3PGLU ABETA antibodies + a BACE inhibitor | 伊莱利利公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-103923101-B | Synthetic method of prasugrel | 湖南方盛制药股份有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-105801550-A | Novel benzopyran kinase modulators | 理森制药股份公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-102812013-B | Novel benzopyran kinase modulators | RHIZEN PHARMACEUTICALS S.A. (CH) | 2016-05-25 | — | — | CN | disclosed |
| CN-105503828-A | Preparation method of fumarate of pyrrole derivatives | BEIJING KANG LISHENG PHARMACEUTICAL TECH DEV CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-101268067-A | Indol-3-yl-carbonyl-piperidine-benzimidazole derivatives as V1A receptor antagonists | HOFFMANN LA ROCHE (CH) | 2008-09-17 | — | — | CN | disclosed |
| CN-100389113-C | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2008-05-21 | — | — | CN | disclosed |
| CN-1630650-A | Nitrogen-containing heterocyclic compound and drug containing same | EISAI CO LTD (JP) | 2005-06-22 | — | — | CN | disclosed |
| EP-0771196-B1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5717109-A | CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| CN-1128990-A | N-substituted azaheterocyclic carboxylic acids and esters thereof | NOVO NORDISK AS (DK) | 1996-08-14 | — | — | CN | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |