SCHEMBL246473

SCHEMBL246473

O=C(O)CCc1ccccc1F

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 1/20 0.59
KMT2A Q03164 1/20 0.59
FFAR1 O14842 7/20 0.58
FFAR4 Q5NUL3 6/20 0.58
TAAR1 Q96RJ0 1/20 0.54
KEAP1 Q14145 1/20 0.54
PTGER1 P34995 1/20 0.50
PTGER4 P35408 1/20 0.50
PTGER3 P43115 1/20 0.50
PTGER2 P43116 1/20 0.50
TSPO P30536 1/20 0.49
DRD3 P35462 1/20 0.49
CASP3 P42574 1/20 0.48
CASP7 P55210 1/20 0.48
CXCL8 P10145 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444401 1.00 MEN1 (0.59) MEN1ALDH1A1KMT2AFFAR1FFAR4
Acetic Acid SCHEMBL29114584 0.94 MEN1 (0.54) MEN1ALDH1A1KMT2AFFAR1FFAR4
SCHEMBL1265758 0.88 HDAC3 (0.57) MEN1ALDH1A1KMT2AFFAR1FFAR4
SCHEMBL29462363 0.88 HDAC3 (0.57) MEN1ALDH1A1KMT2AFFAR1FFAR4
SCHEMBL7331602 0.85 TAAR1 (0.56) MEN1ALDH1A1KMT2AFFAR1FFAR4
SCHEMBL13492011 0.85 MAPT (0.59) MEN1ALDH1A1KMT2ATAAR1PTGER1
SCHEMBL30427741 0.85 MAPT (0.59) MEN1ALDH1A1KMT2ATAAR1PTGER1
SCHEMBL7341280 0.85 PTGER4 (0.57) MEN1ALDH1A1KMT2AFFAR1FFAR4
SCHEMBL2487912 0.85 MAPT (0.59) MEN1ALDH1A1KMT2ATAAR1PTGER1
SCHEMBL59198 0.84 KEAP1 (0.65) FFAR1FFAR4KEAP1PTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143097-A Beta-carbopol compound, preparation method thereof and application of beta-carbopol compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2023-12-01 CN claimed
EP-2799424-B1 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE LTT BIO PHARMA CO LTD (JP) 2016-08-17 EP claimed
US-9221786-B2 2-fluorophenyl propionic acid derivatives LTT BIO-PHARMA CO., LTD. (JP) 2015-12-29 US claimed
US-20140330026-A1 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES LTT BIO-PHARMA CO., LTD. (JP) 2014-11-06 US claimed
EP-2799424-A1 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE LTT Bio-Pharma Co., Ltd. (JP) 2014-11-05 EP claimed
US-4411974-A FOR NEGATIVE TONERS XEROX CORPORATION (US) 1983-10-25 US claimed
US-12492210-B2 Tricyclic compounds and their use HUTCHISON MEDIPHARMA LIMITED (CN) 2025-12-09 US disclosed
EP-4620949-A1 ACKR3 MODULATORS FOR CARDIOVASCULAR OR ANTIPLATELET THERAPY Eberhard Karls Universität Tübingen (Medizinische Fakultät) (DE) 2025-09-24 EP disclosed
WO-2024204554-A1 SPIROCYCLIC MORPHINAN DERIVATIVE 日本ケミファ株式会社 2024-10-03 WO disclosed
CN-117486890-A Tricyclic compounds and uses thereof 和记黄埔医药(上海)有限公司 2024-02-02 CN disclosed
CN-117486888-A Tricyclic compounds and uses thereof 和记黄埔医药(上海)有限公司 2024-02-02 CN disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-4029681-A 13,14-Didehydro-PG analogs THE UPJOHN COMPANY (US) 1977-06-14 US disclosed
US-4028419-A PROSTAGLANDINS THE UPJOIN COMPANY (US) 1977-06-07 US disclosed
US-4028350-A ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1977-06-07 US disclosed
US-4026909-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-05-31 US disclosed
US-4018803-A 13,14-Didehydro-PG3 compounds THE UPJOHN COMPANY (US) 1977-04-19 US disclosed
US-4016184-A PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1977-04-05 US disclosed
US-4013695-A PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL THE UPJOHN COMPANY (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140330026-A1 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES FPR1, OPRK1, FPR2 MEN1 4256/4885ALDH1A1 57/4885KMT2A 2456/4885
US-12492210-B2 Tricyclic compounds and their use CYP2C8, CYP11B2, CYP3A7 MEN1 2181/4885ALDH1A1 1343/4885KMT2A 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.