Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 13/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403272 | 0.82 | CHRM1 (0.76) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL29627864 | 0.82 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7323716 | 0.82 | CHRM1 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL11834495 | 0.78 | CHRM1 (0.62) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL9383698 | 0.77 | CHRM1 (0.68) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL21129811 | 0.77 | CHRM1 (0.64) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL11824724 | 0.75 | CHRM1 (0.70) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7330628 | 0.75 | ALOX12 (1.00) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7330330 | 0.75 | CHRM1 (0.71) | CHRM1ALDH1A1PKMHTTNPSR1 | |
| SCHEMBL7322840 | 0.73 | CHRM1 (0.77) | CHRM1ALDH1A1PKMHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902794-A | Triazolo-benzodiazepines | THE UPJOHN COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-3987052-A | SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |