Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.65 |
| ▸ | BCL2 | P10415 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377248 | 1.00 | ACE (0.65) | ACEBCL2PTPN1HDAC8ITGB3 | |
| SCHEMBL1791039 | 0.90 | ACE (0.78) | ACERENCTSSCTSLCTSB | |
| SCHEMBL7326335 | 0.90 | ACE (0.78) | ACERENCTSSCTSLCTSB | |
| SCHEMBL13537626 | 0.88 | BCL2 (0.62) | ACEBCL2PTPN1HDAC8ITGB3 | |
| SCHEMBL7320039 | 0.88 | ACE (0.58) | ACEBCL2PTPN1HDAC8ITGB3 | |
| SCHEMBL2891538 | 0.88 | PTPN1 (0.73) | ACEBCL2PTPN1HDAC8ITGB3 | |
| SCHEMBL193473 | 0.88 | PTPN1 (0.73) | ACEBCL2PTPN1HDAC8ITGB3 | |
| SCHEMBL193474 | 0.88 | PTPN1 (0.73) | ACEBCL2PTPN1HDAC8ITGB3 | |
| SCHEMBL3500186 | 0.86 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B | |
| SCHEMBL3350988 | 0.86 | BCL2 (0.64) | BCL2PTPN1HDAC8ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |