Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.78 |
| ▸ | CTSS | P25774 | 6/20 | 0.62 |
| ▸ | CTSK | P43235 | 5/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | REN | P00797 | 2/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1791039 | 1.00 | ACE (0.78) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7323726 | 0.92 | ACE (0.71) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL10377248 | 0.90 | ACE (0.65) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL7332128 | 0.90 | ACE (0.65) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL10536264 | 0.89 | ACE (0.70) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL17688687 | 0.89 | ACE (0.70) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL6899564 | 0.89 | CTSS (0.65) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL1793542 | 0.88 | ACE (1.00) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL1793539 | 0.88 | ACE (1.00) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL27669147 | 0.87 | ACE (0.71) | ACECTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039596-A | Preparation method in conjunction with the peptide of retroviral Protease | SMITHKLINE BECKMAN CORP (US) | 1990-02-14 | — | — | CN | disclosed |
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |