Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334478 | 0.92 | RXRA (0.32) | ITGB3ITGA2BNUDT1CYP1A2CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL7333191 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BCYP1A2CYP2C19GABRA1 | |
| SCHEMBL7328314 | 0.91 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL7332354 | 0.90 | ITGB3 (0.31) | ITGB3ITGA2B | |
| SCHEMBL7329669 | 0.89 | PTGDR2 (0.32) | ITGB3ITGA2B | |
| SCHEMBL7330443 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BNUDT1CYP1A2CYP2C19 | |
| SCHEMBL7334599 | 0.84 | RXRA (0.31) | — | |
| SCHEMBL7331753 | 0.83 | MDM2 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL7334476 | 0.83 | ITGB3 (0.37) | ITGB3ITGA2BCYP1A2CYP2C19 | |
| SCHEMBL7328779 | 0.83 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663166-A | ANTICOAGULANTS OF 1,4-BENZODIAZEPINE-2,5-DIONE AND 2-BENZOAZEPINE-1,4-DIONE DERIVATIVES; PREVENTS FIBRINOGEN BINDING NECESSARY FOR PLATELET AGGREGATION; SIDE EFFECT REDUCTION, E.G. EXCESSIVE BLEEDING | GENENTECH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1993008174-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1993-04-29 | — | — | WO | disclosed |