Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 8/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | MMP3 | P08254 | 10/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338631 | 0.80 | CA1 (0.44) | CA1CA2CA9MMP3CASP6 | |
| SCHEMBL7339581 | 0.79 | MMP3 (0.52) | CA1CA2MMP3MMP1MMP2 | |
| SCHEMBL7341498 | 0.78 | CA1 (0.44) | CA1CA2CA9MMP3CASP6 | |
| SCHEMBL7332421 | 0.74 | CA1 (0.41) | CA1CA2CA9MMP3CASP6 | |
| SCHEMBL6950585 | 0.72 | MMP3 (0.60) | CA1CA2CA9MMP3MMP1 | |
| SCHEMBL6956799 | 0.72 | MMP3 (0.60) | CA1CA2CA9MMP3MMP1 | |
| SCHEMBL6950588 | 0.72 | MMP3 (0.60) | CA1CA2CA9MMP3MMP1 | |
| SCHEMBL7492356 | 0.72 | CA1 (0.59) | CA1CA2CA9MMP3CASP6 | |
| SCHEMBL7492352 | 0.72 | CA1 (0.59) | CA1CA2CA9MMP3CASP6 | |
| SCHEMBL7338621 | 0.71 | MMP3 (0.47) | CA1CA2CA9MMP3CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |