Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 15/20 | 0.52 |
| ▸ | MMP1 | P03956 | 9/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333445 | 0.82 | MMP3 (0.61) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7333228 | 0.79 | CA1 (0.44) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6959258 | 0.77 | MMP3 (0.62) | MMP3MMP1MMP2 | |
| SCHEMBL6959253 | 0.77 | MMP3 (0.62) | MMP3MMP1MMP2 | |
| SCHEMBL7345089 | 0.76 | MMP3 (0.55) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6952093 | 0.76 | MMP3 (0.69) | MMP3MMP1MMP2 | |
| SCHEMBL6950694 | 0.75 | MMP3 (0.67) | MMP3MMP1MMP2 | |
| SCHEMBL6950696 | 0.75 | MMP3 (0.67) | MMP3MMP1MMP2 | |
| SCHEMBL7339565 | 0.74 | MMP3 (0.54) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL7335781 | 0.73 | MMP3 (0.53) | MMP3MMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847148-A | Thiadiazole derivatives useful for the treatment of diseases related to connective tissue degradation | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-08 | — | — | US | disclosed |