SCHEMBL733345

SCHEMBL733345

CCN(CC)C(=O)C1CC[C@H]2[C@@H]3CCC4N(C)C(=O)CC[C@]4(C)[C@@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 1/20 1.00
SRD5A2 P31213 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3367052 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL11154269 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL852296 1.00 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL5908153 0.89 SRD5A2 (0.80) SRD5A1SRD5A2
SCHEMBL7000399 0.89 SRD5A2 (0.80) SRD5A1SRD5A2
SCHEMBL11141410 0.88 SRD5A1 (0.79) SRD5A1SRD5A2
SCHEMBL11141415 0.88 SRD5A1 (0.79) SRD5A1SRD5A2
SCHEMBL11139621 0.87 SRD5A1 (0.76) SRD5A1SRD5A2
SCHEMBL11139619 0.87 SRD5A1 (0.76) SRD5A1SRD5A2
SCHEMBL9022351 0.85 SRD5A1 (0.74) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459187-B1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH OLSEN ELISE (US) 2021-01-06 EP claimed
US-20190314259-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH DUKE UNIVERSITY 2019-10-17 US claimed
EP-1175202-B3 ANTI-DANDRUFF AND CONDITIONING SHAMPOOS CONTAINING POLYALKYLENE GLYCOLS AND CATIONIC POLYMERS PROCTER & GAMBLE (US) 2014-03-05 EP claimed
EP-1181008-B1 ANTI-DANDRUFF AND CONDITIONING SHAMPOOS CONTAINING CERTAIN CATIONIC POLYMERS PROCTER & GAMBLE (US) 2011-06-22 EP claimed
EP-1175202-B1 ANTI-DANDRUFF AND CONDITIONING SHAMPOOS CONTAINING POLYALKYLENE GLYCOLS AND CATIONIC POLYMERS PROCTER & GAMBLE (US) 2004-09-15 EP claimed
EP-1098626-B1 METHOD FOR REGULATING HAIR GROWTH UNIV TEXAS SOUTHWESTERN MED CT (US) 2004-05-06 EP claimed
US-6649155-B1 Cationic guar THE PROCTER & GAMBLE COMPANY 2003-11-18 US claimed
US-20030114526-A1 Administration to a human for hair growth a formulation containing a compound selected from lupane triterpenes and derivatives, derivatives of oleanane triterpenes, derivatives of ursane derivatives or salts and mixtures; antialopecia PROCTER & GAMBLE TO THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER 2003-06-19 US claimed
US-6451777-B1 Method for regulating hair growth THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER 2002-09-17 US claimed
US-6451300-B1 ANTI-DANDRUFF EFFICACY AND CONDITIONING, AND A METHOD OF CLEANSING AND CONDITIONING THE HAIR COMPRISING APPLYING TO THE HAIR AND SCALP AN EFFECTIVE AMOUNT OF SAID COMPOSITIONS. THE PROCTER & GAMBLE COMPANY 2002-09-17 US claimed
WO-1992021322-A1 COSMETIC OR PHARMACEUTICAL, PARTICULARLY DERMATOLOGICAL, COMPOSITION CONTAINING A PRUNELLA EXTRACT LVMH RECHERCHE (FR) 1992-12-10 WO claimed
WO-1992016186-A1 COSMETIC OR PHARMACEUTICAL, ESPECIALLY DERMATOLOGICAL, COMPOSITION,CONTAINING OXYACANTHINE, IN PARTICULAR FOR STIMULATING HAIR GROWTH OR RETARDING HAIR LOSS LVMH RECHERCHE (FR) 1992-10-01 WO claimed
WO-1992009262-A1 USE OF MEDICAGO SAPONINS FOR THE PREPARATION OF COSMETIC OR PHARMACEUTICAL COMPOSITIONS, DERMATOLOGICAL COMPOSITIONS IN PARTICULAR, HELPING RENEW THE EPIDERMIS, STIMULATING REGROWTH OF HAIR, OR DELAYING HAIR LOSS LVMH RECHERCHE (FR) 1992-06-11 WO claimed
EP-0486595-A1 SKIN PIGMENT COMPOSITION CONTAINING A COLEUS EXTRACT. LVMH RECH (FR) 1992-05-27 EP claimed
WO-1991002516-A1 SKIN PIGMENT COMPOSITION CONTAINING A COLEUS EXTRACT LVMH RECHERCHE (FR) 1991-03-07 WO claimed
US-4885289-A APPLYING ANTIANDROGEN TO SKIN GILLETTE COMPANY 1989-12-05 US claimed
EP-0004949-B1 4-AZA-17-SUBSTITUTED-5-ALPHA-ANDROSTAN-3-ONE, THEIR A AND D HOMO ANALOGS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1983-09-21 EP claimed
US-4377584-A 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors MERCK & CO., INC. (US) 1983-03-22 US claimed
US-4220775-A Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors MERCK & CO., INC. (US) 1980-09-02 US claimed
EP-0004949-A1 4-Aza-17-substituted-5-alpha-androstan-3-one, their A and D homo analogs, process for their preparation and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1979-10-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114526-A1 Administration to a human for hair growth a formulation containing a compound selected from lupane triterpenes and derivatives, derivatives of oleanane triterpenes, derivatives of ursane derivatives or salts and mixtures; antialopecia LSS, CUTA, NR5A1 SRD5A1 47/4885SRD5A2 26/4885
US-20190314259-A1 COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH PTGIR, MC1R, PTGFR SRD5A1 374/4885SRD5A2 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.