Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377728 | 0.90 | TRHR (0.49) | TRHR | |
| SCHEMBL7375258 | 0.89 | TRHR (0.48) | TRHR | |
| SCHEMBL7324766 | 0.85 | TRHR (0.53) | TRHR | |
| SCHEMBL7332746 | 0.85 | TRHR (0.55) | TRHR | |
| SCHEMBL10345482 | 0.84 | TRHR (0.55) | TRHR | |
| SCHEMBL10345951 | 0.84 | TRHR (0.54) | TRHR | |
| Azetirelin SCHEMBL250397 | 0.83 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL7265691 | 0.83 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL10703548 | 0.83 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL4958204 | 0.83 | TRHR (0.62) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384380-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-06-19 | — | — | EP | claimed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | claimed |
| EP-0384380-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-06-19 | — | — | EP | disclosed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |