Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333561 | 0.84 | DRD2 (0.36) | DRD2ALDH1A1 | |
| SCHEMBL7333568 | 0.83 | DRD2 (0.34) | ACACBDRD2ALDH1A1 | |
| SCHEMBL7799999 | 0.82 | DRD3 (0.34) | DRD2ALDH1A1 | |
| SCHEMBL7800001 | 0.82 | DRD3 (0.34) | DRD2ALDH1A1 | |
| SCHEMBL7363376 | 0.71 | DRD3 (0.40) | DRD2ALDH1A1 | |
| SCHEMBL7363383 | 0.69 | DRD3 (0.39) | DRD2ALDH1A1 | |
| SCHEMBL7363381 | 0.69 | DRD3 (0.39) | DRD2ALDH1A1 | |
| SCHEMBL10895464 | 0.67 | ALDH1A1 (0.58) | DRD2ALDH1A1 | |
| SCHEMBL7329975 | 0.61 | DRD2 (0.36) | DRD2 | |
| Hydrochloric Acid SCHEMBL7329360 | 0.60 | DRD2 (0.40) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781126-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008228-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |