Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325575 | 0.74 | CTSB (0.50) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL8346816 | 0.72 | CTSL (0.62) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL17704241 | 0.72 | CTSL (0.62) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL6436627 | 0.72 | CTSL (0.62) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL7330793 | 0.71 | ELANE (0.49) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL18134966 | 0.71 | CTSL (0.60) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL10885791 | 0.71 | CTSL (0.60) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL5338870 | 0.71 | CTSL (0.60) | CASP3CASP1CASP7CASP6CASP8 | |
| SCHEMBL14902868 | 0.71 | CTSL (0.60) | CCR1CASP3CASP1CASP7CASP6 | |
| SCHEMBL5120950 | 0.71 | CTSL (0.60) | CASP3CASP1CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369391-A2 | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |