Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6954388 | 0.99 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL6947178 | 0.89 | KDM4E (0.52) | ITGB3ITGA2BKDM4EALDH1A1GLA | |
| SCHEMBL10705202 | 0.76 | AKT1 (0.67) | KDM4EALDH1A1GLAGAAHPGD | |
| Hydrochloric Acid SCHEMBL6960084 | 0.75 | ITGB3 (0.47) | ITGB3ITGA2BF2 | |
| SCHEMBL6954418 | 0.74 | MAOB (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL6604268 | 0.70 | MAOB (0.82) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL11105397 | 0.70 | AKT1 (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL11112855 | 0.69 | AKT1 (0.69) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL9636955 | 0.67 | CYSLTR2 (0.54) | MAOB | |
| SCHEMBL7362305 | 0.67 | ITGB3 (0.68) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022288-A1 | GLYCOPROTEIN IIb/IIIa ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |