Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403375 | 0.89 | AOC3 (0.48) | ITGB3ITGA2BGAAALDH1A1MAPT | |
| SCHEMBL7398346 | 0.89 | SMN1; SMN2 (0.44) | ITGB3ITGA2BGAAALDH1A1MAPT | |
| SCHEMBL7393253 | 0.87 | ITGB3 (0.56) | ITGB3ITGA2BGAAALDH1A1HRH3 | |
| SCHEMBL7398343 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BGAAALDH1A1MAPT | |
| SCHEMBL7401164 | 0.82 | HRH3 (0.42) | ITGB3ITGA2BGAAMAPTHRH3 | |
| SCHEMBL27442363 | 0.81 | HRH3 (0.49) | HRH3 | |
| SCHEMBL7397030 | 0.80 | AOC3 (0.47) | ITGB3ITGA2BGAAALDH1A1MAPT | |
| SCHEMBL7395114 | 0.79 | SMN1; SMN2 (0.55) | ITGB3ITGA2BGAAALDH1A1HRH3 | |
| SCHEMBL7402670 | 0.78 | ITGB3 (0.45) | ITGB3ITGA2BGAAALDH1A1HRH3 | |
| SCHEMBL8633587 | 0.78 | ITGB3 (0.45) | ITGB3ITGA2BGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | claimed |
| EP-0691959-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-17 | — | — | EP | claimed |
| WO-1994022834-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | claimed |