Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395114 | 0.91 | SMN1; SMN2 (0.55) | SMN1; SMN2ITGB3ITGA2BGRM5HRH3 | |
| SCHEMBL7334455 | 0.89 | ITGB3 (0.51) | SMN1; SMN2ARITGB3ITGA2BHRH3 | |
| SCHEMBL7403375 | 0.85 | AOC3 (0.48) | ARITGB3ITGA2BHRH3GAA | |
| SCHEMBL7401164 | 0.84 | HRH3 (0.42) | ARITGB3ITGA2BHRH3GAA | |
| SCHEMBL7336053 | 0.80 | ITGB3 (0.40) | ITGB3ITGA2BGRM5HRH3GAA | |
| SCHEMBL7393253 | 0.79 | ITGB3 (0.56) | SMN1; SMN2ITGB3ITGA2BHRH3GAA | |
| SCHEMBL7398338 | 0.79 | BRD4 (0.49) | ITGB3ITGA2BHRH3METAP1MAPT | |
| SCHEMBL7401777 | 0.78 | PPARG (0.45) | SMN1; SMN2ITGB3ITGA2BHRH3MEN1 | |
| SCHEMBL7402995 | 0.78 | NPY2R (0.43) | ITGB3ITGA2BHRH3GAAMEN1 | |
| SCHEMBL7397030 | 0.77 | AOC3 (0.47) | ITGB3ITGA2BHRH3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825184-B1 | Heterocyclic derivatives as platelet aggregation inhibitors | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| CN-1120334-A | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LTD (GB) | 1996-04-10 | — | — | CN | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |