Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29393267 | 0.96 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL11299600 | 0.90 | ALDH1A1 (0.52) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL8508358 | 0.89 | ALDH1A1 (0.51) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL9420221 | 0.89 | ALDH1A1 (0.54) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL9586772 | 0.88 | ALDH1A1 (0.56) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL10947367 | 0.88 | ALDH1A1 (0.53) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL11266521 | 0.88 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL10981472 | 0.87 | ALDH1A1 (0.49) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL2042610 | 0.87 | MAPT (0.70) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 | |
| SCHEMBL11310987 | 0.87 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| EP-1893016-B1 | WATER-IN-OIL SUSPOEMULSIONS | BAYER IP GMBH (DE) | 2017-09-13 | — | — | EP | disclosed |
| EP-1651039-B1 | OIL SUSPENSION CONCENTRATE CONTAINING DIFLUFENICAN | BAYER IP GMBH (DE) | 2017-01-04 | — | — | EP | disclosed |
| EP-1928232-B1 | SOLID FORMULATION | BAYER IP GMBH (DE) | 2016-07-13 | — | — | EP | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2908639-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-9102623-B2 | Pyridinecarboxamides, useful-plant-protecting composition comprising them and processes for their preparation and their use | BAYER CROPSCIENCE AG (DE) | 2015-08-11 | — | — | US | disclosed |
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-1571908-B1 | OIL SUSPENSION CONCENTRATE | BAYER CROPSCIENCE AG (DE) | 2014-12-17 | — | — | EP | disclosed |
| WO-2014060502-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| WO-1992016101-A1 | MAIZE CAPABLE OF RESISTING HERBICIDES OF THE ARYLOXY-PHENOXY-ALKANE CARBOXYLIC ACID TYPE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-01 | — | — | WO | disclosed |
| EP-0501986-A1 | ISOXAZOLINES, METHOD OF PREPARATION THEREOF, AND THEIR USE AS PLANT-PROTECTION AGENTS | Hoechst Schering AgrEvo GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |
| EP-0492366-A2 | New 5-chloroquinolin-8-oxyalkanecarbonic acid derivatives, process for their preparation and their use as antidotes for herbicides | Hoechst Schering AgrEvo GmbH (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0476555-A2 | Synergistic herbicidal agents | Hoechst Schering AgrEvo GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |
| WO-1992003053-A1 | PLANT PROTECTING AGENTS CONTAINING ISOXAZOLINE OR ISOTHIAZOLINE AND NEW ISOXAZOLINES AND ISOTHIAZOLINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-05 | — | — | WO | disclosed |
| WO-1991018907-A1 | PLANT-PROTECTING SUBSTITUTED ISOXAZOLINES, ISOXAZOLES, ISOTHIAZOLINES AND ISOTHIAZOLES, PROCESS FOR PRODUCING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-12 | — | — | WO | disclosed |
| WO-1991008202-A1 | ISOXAZOLINES, METHOD OF PREPARATION THEREOF, AND THEIR USE AS PLANT-PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-13 | — | — | WO | disclosed |
| EP-0417626-A2 | Plant protection agents containing N-arylhydrazones and N-arylhydrazones | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0046467-B1 | QUINOXALINE DERIVATIVES AND HERBICIDAL COMPOSITION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-27 | — | — | EP | disclosed |
| EP-0046467-A1 | Quinoxaline derivatives and herbicidal composition | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | MAPT 4268/4885SMN1; SMN2 4330/4885ALDH1A1 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.