Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 10/20 | 0.56 |
| ▸ | KDR | P35968 | 8/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955095 | 0.77 | KDR (0.84) | PDGFRBKDRHSP90AB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3536379 | 0.73 | KDR (0.64) | PDGFRBKDRHSP90AB1ALDH1A1HTT | |
| SCHEMBL21326025 | 0.73 | HSP90AB1 (0.68) | HSP90AB1 | |
| SCHEMBL29586646 | 0.73 | HSP90AB1 (0.68) | HSP90AB1 | |
| SCHEMBL17620622 | 0.72 | PDGFRB (1.00) | PDGFRBKDRMAPT | |
| SCHEMBL9955257 | 0.72 | PDGFRB (0.71) | PDGFRBKDRHSP90AB1 | |
| SCHEMBL3531326 | 0.71 | PDGFRB (0.60) | PDGFRBKDR | |
| SCHEMBL17635120 | 0.70 | PDGFRB (1.00) | PDGFRBKDR | |
| SCHEMBL17635122 | 0.70 | KDR (1.00) | PDGFRBKDRHSP90AB1 | |
| SCHEMBL21326011 | 0.69 | PDGFRB (0.58) | PDGFRBHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405848-A | Substituted thiazolylaminotetrahydropyridopyrimidines derivatives useful as platelet aggregation inhibitors | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-04-11 | — | — | US | claimed |