Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326237 | 0.85 | PDE4A (0.37) | HPGDSMN1; SMN2 | |
| SCHEMBL7332932 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1HTTHTR2A | |
| SCHEMBL3054218 | 0.74 | HTT (0.49) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL9789206 | 0.72 | MCL1 (0.35) | MTNR1AMTNR1BALDH1A1HTTHPGD | |
| SCHEMBL3054263 | 0.71 | HTT (0.48) | MTNR1AMTNR1BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8078291 | 0.70 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3048958 | 0.70 | HDAC6 (0.52) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL13087200 | 0.69 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1HPGDHTR2A | |
| SCHEMBL3057582 | 0.69 | HTT (0.46) | MTNR1AMTNR1BALDH1A1HTT | |
| SCHEMBL3048558 | 0.68 | MTNR1A (0.54) | MTNR1AMTNR1BALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102901-A | 5-hydroxytrypamine receptor antaonists | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-04-07 | — | — | US | disclosed |
| EP-0393766-A2 | New 3-N substituted carbamoyl-indole derivatives | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-10-24 | — | — | EP | disclosed |