SCHEMBL733492

SCHEMBL733492

Brc1cc(I)c(Br)cc1I

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CHEK1 O14757 1/20 0.33
DAPK3 O43293 1/20 0.33
RET P07949 1/20 0.33
PDGFRB P09619 1/20 0.33
PIM1 P11309 1/20 0.33
PDGFRA P16234 1/20 0.33
KDR P35968 1/20 0.33
MAPK8 P45983 1/20 0.33
RPS6KA3 P51812 1/20 0.33
LIMK1 P53667 1/20 0.33
TYRO3 Q06418 1/20 0.33
MAPK14 Q16539 1/20 0.33
LRRK2 Q5S007 1/20 0.33
AURKB Q96GD4 1/20 0.33
AHR P35869 1/20 0.32
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2697849 0.88 CA1 (0.32) APEX1CA1CA2CA9CHEK1
SCHEMBL16193369 0.87
SCHEMBL734615 0.83 AHR (0.39) APEX1CA1CA2CA9CHEK1
SCHEMBL11983609 0.82
SCHEMBL19417353 0.82 ALDH1A1 (0.32) CHEK1DAPK3RETPDGFRBPIM1
SCHEMBL19570526 0.82 BCHE (0.33) CHEK1DAPK3RETPDGFRBPIM1
SCHEMBL21142526 0.77 ACHE (0.32) CA1CA2CA9
SCHEMBL21356327 0.77 AHR (0.40) CA1CA2CA9AHR
SCHEMBL18015461 0.77 TSHR (0.38) CHEK1DAPK3RETPDGFRBPIM1
SCHEMBL13145674 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684125-A Macrocyclic cyclic molecule of modified carboxylic ester, and preparation method and application thereof 合肥芯旷电子科技有限公司 2025-03-25 CN claimed
CN-119092798-A MOF-based solid electrolyte composite membrane and preparation method and application thereof 浙江大学杭州国际科创中心 2024-12-06 CN claimed
CN-119060276-A Irreversible bond connected self-polymerization covalent organic framework material, composite electrocatalyst and preparation method and application thereof 南开大学 2024-12-03 CN claimed
CN-115959969-B Synthesis method of 1, 4-dibromo-2, 5-diiodobenzene and homologs thereof 安徽科技学院 2024-07-26 CN claimed
CN-117285454-A Synthesis method of indole derivative and benzodipyrrole derivative 南京邮电大学 2023-12-26 CN claimed
CN-117143348-A Metal-MOF composite material and preparation method and application thereof 浙江大学杭州国际科创中心 2023-12-01 CN claimed
CN-115959969-A Synthetic method of 1,4-dibromo-2,5-diiodobenzene and homolog thereof 安徽科技学院 2023-04-14 CN claimed
CN-114057606-B Organic luminescent material containing terphenyl, preparation method and application 华南理工大学 2023-04-07 CN claimed
CN-111099959-B Industrial production method of 1, 4-dibromo-2, 5-diiodobenzene 西安瑞联新材料股份有限公司 2022-09-02 CN claimed
CN-112537996-B Method for green synthesis of 2, 5-dibromo-1, 4-diiodobenzene intermediate 大连金点生物科技有限公司 2022-05-27 CN claimed
CN-111099959-A Industrial production method of 1, 4-dibromo-2, 5-diiodobenzene 西安瑞联新材料股份有限公司 2020-05-05 CN claimed
CN-108558948-B Diphospha-containing heterocyclic cyclopentadiene fused ring organic electroluminescent compound and synthesis method thereof 河南省科学院化学研究所有限公司 2020-04-07 CN claimed
CN-110627611-A Method for synthesizing 1, 4-dibromo-2, 5-diiodobenzene 山东瑞辰新材料有限公司 2019-12-31 CN claimed
WO-2019218360-A1 AGGREGATION-INDUCED BLUE LIGHT EMITTING MATERIAL AND PREPARATION METHOD THEREFOR, AND DISPLAY DEVICE 深圳市柔宇科技有限公司 (CN) 2019-11-21 WO claimed
CN-104211911-A Conjugated polymer, preparation method, and applications thereof OCEANS KING LIGHTING SCIENCE 2014-12-17 CN claimed
CN-104211920-A Conjugated polymer, preparation method and applications thereof OCEANS KING LIGHTING SCIENCE 2014-12-17 CN claimed
CN-104211919-A Conjugated polymer, preparation method, and applications thereof OCEANS KING LIGHTING SCIENCE 2014-12-17 CN claimed
CN-104211914-A Conjugated polymer, preparation method, and applications thereof OCEANS KING LIGHTING SCIENCE 2014-12-17 CN claimed
CN-104211910-A Conjugated polymer, preparation method and applications thereof OCEANS KING LIGHTING SCIENCE 2014-12-17 CN claimed
WO-2014171931-A1 GRAPHENE NANORIBBONS AS SEMICONDUCTORS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-10-23 WO claimed