Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.50 |
| ▸ | OXTR | P30559 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336360 | 0.90 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL7333134 | 0.89 | AVPR2 (0.57) | AVPR2AVPR1AOXTRAKT1 | |
| SCHEMBL7344791 | 0.89 | AVPR2 (0.59) | AVPR2AVPR1AOXTRLMNA | |
| SCHEMBL7366872 | 0.89 | AVPR2 (0.56) | AVPR2AVPR1AOXTRAKT1 | |
| SCHEMBL7336470 | 0.87 | AVPR2 (0.52) | AVPR2AVPR1AOXTRAKT1 | |
| SCHEMBL7341289 | 0.84 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL7335578 | 0.82 | AVPR2 (0.57) | AVPR2AVPR1AOXTRAKT1 | |
| SCHEMBL7334113 | 0.82 | AVPR2 (0.54) | AVPR2AVPR1AOXTRLMNA | |
| SCHEMBL7339535 | 0.81 | AVPR2 (0.63) | AVPR2AVPR1AOXTRLMNA | |
| SCHEMBL7335725 | 0.79 | AVPR2 (0.67) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | claimed |
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |