Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295327 | 1.00 | TSHR (0.30) | TSHR | |
| SCHEMBL7295356 | 1.00 | TSHR (0.30) | TSHR | |
| SCHEMBL7295329 | 1.00 | TSHR (0.30) | TSHR | |
| SCHEMBL7332966 | 0.76 | TDP1 (0.38) | TSHR | |
| SCHEMBL7332971 | 0.76 | TDP1 (0.38) | TSHR | |
| SCHEMBL14639737 | 0.76 | TDP1 (0.38) | TSHR | |
| SCHEMBL9501178 | 0.76 | CHRNB2 (0.40) | — | |
| SCHEMBL7336141 | 0.76 | TDP1 (0.38) | TSHR | |
| SCHEMBL28439943 | 0.73 | MEN1 (0.34) | — | |
| SCHEMBL11960899 | 0.73 | SIGMAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583248-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0512343-B1 | Amino acid derivatives and their use as anti-viral agents | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | EP | disclosed |
| US-5430041-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |