Styrene

Styrene

SCHEMBL73353

C1=Cc2cccc3cccc1c23.C=Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
TSHR P16473 4/20 0.56
TDP1 Q9NUW8 2/20 0.36
TP53 P04637 2/20 0.36
HSD17B10 Q99714 4/20 0.33
HPGD P15428 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CYP1A2 P05177 2/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
ATM Q13315 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP1B1 Q16678 1/20 0.33
THRB P10828 1/20 0.32
RELA Q04206 1/20 0.31
CES2 O00748 1/20 0.31
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL15048584 0.86 ALDH1A1 (0.41) ALDH1A1TSHRHPGDL3MBTL1MEN1
4-Vinylphenol SCHEMBL766769 0.83 ALDH1A1 (0.39) ALDH1A1TSHRTDP1L3MBTL1LMNA
Pyrene SCHEMBL4936826 0.83 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53HSD17B10
Styrene SCHEMBL6005255 0.83 ALDH1A1 (0.74) ALDH1A1TSHRTDP1TP53L3MBTL1
Butadiene SCHEMBL9296369 0.81 ALDH1A1 (0.41) ALDH1A1TSHRTP53HSD17B10HPGD
Benzene SCHEMBL27938048 0.80 ALDH1A1 (0.50) ALDH1A1TSHRTDP1TP53HSD17B10
Styrene SCHEMBL27881925 0.79 ALDH1A1 (0.61) ALDH1A1TSHRTDP1TP53HSD17B10
SCHEMBL5376307 0.78 TP53 (0.35) ALDH1A1TSHRTDP1TP53
Naphthalene SCHEMBL28250282 0.78 ALDH1A1 (0.47) ALDH1A1TSHRTDP1TP53HSD17B10
Ethylene SCHEMBL28031639 0.78 ALDH1A1 (0.47) ALDH1A1TSHRTDP1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129086-B2 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20090247701-A1 COMPOSITION FOR FORMING AN INSULATING FILM FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-5521039-A NOVEL CHARAGE GENERATING MATERIAL IS DISAZO COMPOUND CONTAINING ALKYNE GROUP FUJI PHOTO FILM CO., LTD. (JP) 1996-05-28 US disclosed
EP-0425224-A1 An electrophotograhic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1991-05-02 EP disclosed
EP-0425223-A1 An electrophotographic lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1991-05-02 EP disclosed
US-4756993-A Light scattering layer comprises inorganic fine powder and binder or light absorbing layer comprising near infrared absorbing dye and binder FUJI PHOTO FILM CO., LTD. (JP) 1988-07-12 US disclosed
EP-0131140-A2 Photoconductive compositions and electrophotographic photoreceptors using the same FUJI PHOTO FILM CO., LTD. (JP) 1985-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297979-A1 Polymerizable compound, polymer, positive resist composition, and patterning process using the same PRRC2A, PUF60, POLR2B ALDH1A1 3867/4885TSHR 4785/4885TDP1 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.