Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 8/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 5/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339153 | 0.84 | ACE (0.41) | AGTR2ACELMNA | |
| SCHEMBL7339144 | 0.84 | ACE (0.41) | AGTR2ACELMNA | |
| SCHEMBL7335472 | 0.83 | ACE (0.49) | CTSLACECMA1 | |
| SCHEMBL7335961 | 0.80 | BCL9 (0.38) | LMNACACNA1B | |
| SCHEMBL13007477 | 0.77 | ALDH1A1 (0.42) | LMNA | |
| SCHEMBL3774280 | 0.76 | CACNA1B (0.43) | CTSLCACNA1B | |
| SCHEMBL3774284 | 0.76 | CACNA1B (0.43) | CTSLCACNA1B | |
| SCHEMBL7330332 | 0.74 | F2 (0.36) | LMNA | |
| SCHEMBL2760309 | 0.73 | NPC1 (0.53) | — | |
| SCHEMBL7337728 | 0.73 | NPC1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371091-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-12-06 | — | — | US | disclosed |