Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27354856 | 0.83 | GRM2 (0.39) | THRATHRBSLC7A5MAOBMAOA | |
| SCHEMBL3911621 | 0.83 | ALDH1A1 (0.45) | THRATHRBMAOBMAOATACR1 | |
| SCHEMBL13039762 | 0.81 | THRA (0.43) | THRATHRBMAOBMAOATACR1 | |
| SCHEMBL6645967 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SYK | |
| SCHEMBL6597806 | 0.79 | ALDH1A1 (0.61) | THRATHRBMAOBMAOAALDH1A1 | |
| SCHEMBL275395 | 0.79 | SYK (0.46) | TACR1ALDH1A1SYK | |
| SCHEMBL9943376 | 0.78 | TP53 (0.37) | SLC7A5ALDH1A1SYK | |
| SCHEMBL2540267 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SYK | |
| SCHEMBL6180823 | 0.78 | SLC7A5 (0.45) | THRATHRBSLC7A5MAOBMAOA | |
| SCHEMBL21533310 | 0.78 | SLC7A5 (0.65) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |