Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338466 | 0.89 | DCTPP1 (0.41) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7338349 | 0.89 | DCTPP1 (0.41) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7338395 | 0.88 | DCTPP1 (0.42) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7329929 | 0.85 | DCTPP1 (0.40) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7337801 | 0.83 | DCTPP1 (0.40) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7897255 | 0.80 | MAPT (0.40) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7329142 | 0.79 | MAPT (0.39) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7338203 | 0.68 | HSD17B3 (0.42) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7337608 | 0.65 | RAB9A (0.43) | MAPTLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7335512 | 0.65 | DCTPP1 (0.43) | LMNAKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191124-B1 | VIRICIDES | PHARMACIA & UPJOHN COMPANY | 2001-02-20 | — | — | US | disclosed |
| EP-0757692-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029922-A1 | METHANOL DERIVATIVES FOR TREATMENT OF RETROVIRAL INFECTIONS ESPECIALLY HIV INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |