Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780810 | 0.91 | TP53 (0.42) | BRPF1BRD4HTTMAPTHSP90AA1 | |
| SCHEMBL7346417 | 0.90 | TP53 (0.42) | BRPF1BRD4HTTMAPTHSP90AA1 | |
| SCHEMBL7336388 | 0.89 | TP53 (0.39) | BRPF1BRD4HTTMAPTHSP90AA1 | |
| SCHEMBL7345297 | 0.89 | MAPT (0.40) | BRPF1BRD4HTTMAPTHSP90AA1 | |
| SCHEMBL7348212 | 0.89 | IRAK4 (0.39) | BRPF1BRD4HTTMAPTHSP90AA1 | |
| SCHEMBL7780836 | 0.88 | TP53 (0.38) | BRPF1BRD4HTTMAPTHSP90AA1 | |
| SCHEMBL7337787 | 0.88 | ALDH1A1 (0.41) | ALDH1A1POLBHTTMAPTHSP90AA1 | |
| SCHEMBL7348285 | 0.88 | TP53 (0.38) | ALDH1A1BRPF1BRD4HTTMAPT | |
| SCHEMBL7338074 | 0.88 | DRD2 (0.46) | DRD2 | |
| SCHEMBL7343201 | 0.88 | KMT2A (0.40) | ALDH1A1POLBHTTMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |