Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.43 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.43 |
| ▸ | CBX7 | O95931 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336797 | 0.85 | AVPR2 (0.50) | AVPR2AVPR1AAVPR1BPOLBKMT2A | |
| SCHEMBL7475780 | 0.81 | AVPR2 (0.49) | AVPR2AVPR1AAVPR1BPOLBKMT2A | |
| SCHEMBL7340721 | 0.80 | AVPR2 (0.39) | AVPR2AVPR1ACBX7POLBKMT2A | |
| SCHEMBL7962062 | 0.77 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BCBX7KMT2A | |
| SCHEMBL7478475 | 0.75 | CBX7 (0.38) | AVPR2AVPR1ACBX7POLBKMT2A | |
| SCHEMBL7343561 | 0.75 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7999247 | 0.75 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7778565 | 0.74 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BPOLBSMN1; SMN2 | |
| SCHEMBL7778599 | 0.74 | SIGMAR1 (0.37) | AVPR2AVPR1APOLBKMT2AMEN1 | |
| SCHEMBL7336166 | 0.74 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |