Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.49 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639832 | 0.91 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7374740 | 0.87 | LMNA (0.42) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7336797 | 0.84 | AVPR2 (0.50) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7340470 | 0.83 | MEN1 (0.55) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7336809 | 0.81 | AVPR2 (0.43) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7375572 | 0.80 | AVPR2 (0.47) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7346069 | 0.80 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7338979 | 0.80 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 | |
| SCHEMBL7346910 | 0.80 | AVPR2 (0.45) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7999247 | 0.79 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |