Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.37 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339388 | 0.95 | AVPR2 (0.42) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7343339 | 0.93 | AVPR2 (0.39) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7345510 | 0.93 | AVPR2 (0.40) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7335754 | 0.92 | SIGMAR1 (0.40) | SIGMAR1AVPR2AVPR1AWDR5DRD2 | |
| SCHEMBL7340232 | 0.92 | AVPR2 (0.38) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7339422 | 0.92 | AVPR2 (0.41) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7344270 | 0.91 | AVPR2 (0.39) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7338852 | 0.91 | AVPR2 (0.39) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7346725 | 0.91 | AVPR2 (0.39) | SIGMAR1AVPR2AVPR1AAVPR1BWDR5 | |
| SCHEMBL7778595 | 0.91 | AVPR2 (0.42) | SIGMAR1AVPR2AVPR1AAVPR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |